You are here

Patrick (Toby) Coates

Associate Professor Patrick (Toby) Coates is a transplant physician, nephrologist and leading researcher in the field of transplantation.

Publications: 

Increased expression of the glucose-responsive gene RCAN1 causes hypoinsulinemia, B cell dysfunction and diabetes. Peiris H, Raghupathi R, Jessup CF, Zanin MP, Mohanasundaram D, Mackenzie KD, Chataway T, Clarke JN, Brealey J, Coates PT, Pritchard MA, Keating DJEndocrinology 2012

Screening for colorectal cancer and advanced colorectal neoplasia in kidney transplant recipients: a cross-sectional prevalence and diagnostic accuracy study of faecal immunochemical testing for haemoglobin and colonoscopy Collins,M.G., Teo,E., Cole,S.R., Chan,C-Y, McDonald, S.P., Russ,G.R., Young,G.P., Bampton P.A., Coates P.T. BMJ 2012 Jul 25;345:e4657. doi: 10.1136/bmj.e4657

Non-human primate Dendritic cells. Jesudason S, Collins, MG, Rogers, NM, Kireta, S, Coates PT J Leuk Biol 2012:91:217-28

Early exposure of interferon-γ inhibits signal transducer and activator of transcription-6 signalling and nuclear factor κB activation in a short-term monocyte-derived dendritic cell culture promoting 'FAST' regulatory dendritic cells. Rojas-Canales D, Krishnan R, Jessup CF, Coates PT Clin Exp Immunol. 2012 Mar;167(3):447-58

Renal Dendritic Cells Adopt a Pro-Inflammatory Phenotype in Obstructive Uropathy to Activate T Cells, but Do Not Directly Contribute to Fibrosis. Snelgrove SL, Kausman JY, Lo C, Lo C, Ooi JD, Coates PT, Hickey MJ, Holdsworth SR, Kurts C, Engel DR, Kitching AR. Am J Pathol. 2012;180:91-103.

Amelioration of renal ischaemia-reperfusion injury by liposomal delivery curcumin to renal tubular epithelial and antigen presenting cells Rogers NM, Stephenson M, Kitching A, Horowitz J, Coates PT Br J Pharmacol 2012;166:194-209

KHA-CARI adaption of the KDIGO clinical practice guideline for the care of kidney transplant recipients Chadban S, Barraclough K, Campbell, S, Clark C, Coates PT, Cohney S, Cross N, Eris J, Henderson L, Howell M, Isbel N, Kannellis J, Kotwal S, Manley P, Masterson R, Mulley W, Murall K, O'Connell P, Pilmore H, Rogers N, Russ G, Walker R, Webster A, Wiggins K, Wong G, Wyburn K Nephrology 2012;17:204-14

Urinary tubular biomarkers as potential early predictors of renal allograft rejection. Ting YT, Coates PT, Walker RJ, McLellan AD Nephrology 2012;17:11-16

Ultrastructural analysis, zinc transporters and hormones expression in new world primate (Callithrix jacchus) and human pancreatic islets. Mohanasundaram, D, Drogemuller C, Brealey, J, Jessup, CF, Milner, C, Murgia, C, Lang CJ, Milton, A, Zalewski, PD, Russ, GR, Coates PT Gen Comp Endocrinol 2011 Nov 1;174(2):71-9

The Sphingolipid Rheostat: A Potential Target for Improving Pancreatic Islet Survival and Function. Jessup CF, Bonder CS, Pitson SM, Coates PT. Endocr Metab Immune Disord Drug Targets. 2011 Jun 22

Calcium supplements lower bone resorption after renal transplant Yu RW, Faull RJ, Coates PT, Coates PS "Clin Transplant 2011 August 21

Approaching the promise of operational tolerance in clinical transplantation. Bishop GA, Ierino FL, Sharland AF, Hall BM, Alexander SI, Sandrin MS, Coates PT, McCaughan GW.Transplantation. 2011 May 27;91(10):1065-1074

Incorporation of endothelial progenitor cells into mosaic pseudoislets Penko D, Mohanasundaram D, Sen S, Drogemuller C, Mee C, Bonder CS, Coates PT, Jessup CF. Islets. 2011 May 1;3(3):73-9.

Donor human leukocyte antigen specific antibodies predict development and define prognosis in transplant glomerulopathy Eng HS, Bennett G, Chang SH, Dent H, McDonald SP, Bardy P, Coghlan P, Russ GR, Coates PT. Hum Immunol. 2011 May;72(5):386-91.

Endothelial progenitor cells: novel biomarkers and promising cellular therapy for cardiovascular disease Sen S, McDonald SP, Coates PT, Bonder CS. Clin Sci (Lond). 2011 Apr;120(7):263-83. Review.

Curcumin induces maturation resistant dendritic cells that expand T reg cells in vitro and in vivo Rogers NM, Kireta S, Coates PT. Clin Exp Immunol. 2010 Dec;162(3):460-73.

Desensitization for renal transplantation: depletion of donor-specific anti-HLA antibodies, preservation of memory antibodies, and clinical risks. Rogers NM, Eng HS, Yu R, Kireta S, Tsiopelas E, Bennett GD, Brook NR, Gillis D, Russ GR, Coates PT. Transpl Int. 2011 Jan;24(1):21-9.

Gene Therapy to Improve Pancreatic Islet Transplantation for Type 1 Diabetes Mellitus. Hughes A, Jessup C, Drogemuller C, Mohanasundaram D, Milner C, Rojas D, Russ GR, Coates PT. Curr Diabetes Rev. 2010 Sep 1;6(5):274-84. Review

Calcific uremic arteriolopathy--the argument for hyperbaric oxygen and sodium thiosulfate. Rogers NM, Coates PT. Semin Dial. 2010 Jan;23(1):38-42.

Urinary soluble HLA-DR is a potential biomarker for acute renal transplant rejection. Ting YT, Coates PT, Marti HP, Dunn AC, Parker RM, Pickering JW, Jack RW, Kemp RA, Walker RJ, McLellan AD. Transplantation. 2010 May 15;89(9):1071-8.

Propagation and characterisation of dendritic cells from G-CSF mobilised peripheral blood monocytes and stem cells in common marmoset monkeys. Prasad S, Kireta S, Leedham E, Russ GR, Coates PT. J Immunol Methods. 2010 Jan 31;352(1-2):59-70. Epub 2009 Nov 18.

Review article: Kidney dendritic cells: their role in homeostasis, inflammation and transplantation. Rogers NM, Matthews TJ, Kausman JY, Kitching AR, Coates PT. Nephrology (Carlton). 2009 Oct;14(7):625-35. Review. Erratum in: Nephrology (Carlton). 2009 Dec;14(8):769. Kitching, Richard A [corrected to Kitching, A Richard].

Hyperparathyroidism and vitamin D deficiency predispose to bone loss in renal transplant recipients. Lim WH, Coates PS, Russ GR, Coates PT. Transplantation. 2009 Sep 15;88(5):678-83.

Clinical significance of anti-HLA antibodies detected by Luminex: enhancing the interpretation of CDC-BXM and important post-transplantation monitoring tools. Eng HS, Bennett G, Bardy P, Coghlan P, Russ GR, Coates PT. Hum Immunol. 2009 Aug;70(8):595-9. Epub 2009 Jun 12.

Monoclonal antibodies generated by DNA immunization recognize CD2 from a broad range of primates. Brady JL, Mannering SI, Kireta S, Coates PT, Proietto AI, Cowan PJ, D'Apice AJ, Lew AM. Immunol Cell Biol. 2009 Jul;87(5):413-8. Epub 2009 Feb 10

Human leucocyte antigen DQ alpha heterodimers and human leucocyte antigen DR alleles in tubulointerstitial nephritis and uveitis syndrome. Li JY, Yong TY, Bennett G, Barbara JA, Coates PT. Nephrology (Carlton). 2008 Dec;13(8):755-7.

Immunophenotyping of interstitial infiltrate does not distinguish between BK virus nephropathy and acute cellular rejection. Rogers NM, Russ GR, Cooper J, Coates PT. Nephrology (Carlton). 2009 Feb;14(1):118-22. Epub 2009 Jan 8.

Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation. Bonder CS, Sun WY, Matthews T, Cassano C, Li X, Ramshaw HS, Pitson SM, Lopez AF, Coates PT, Proia RL, Vadas MA, Gamble JR. Blood. 2009 Feb 26;113(9):2108-17. Epub 2008 Dec 24.

Eng HS, Bennett G, Tsiopelas E, Lake M, Humphreys I, Chang SH, Coates PT, Russ GR. Am J Transplant. 2008 Nov;8(11):2335-42. Epub 2008 Sep 8.

Parental donors in live-donor kidney transplantation associated with increased rejection rates and reduced glomerular filtration rates. Lim WH, Chang SH, Coates PT, McDonald SP. Transplantation. 2007 Oct 27;84(8):972-80.